How Penicillin Kills Bacteria

Penicillin kills bacteria by interfering with the ability to synthesize cell wall. In this sequence, Eschericia coli were incubated in penicillin for 30 minutes. The bacteria lengthen, but cannot divide. Eventually the weak cell wall ruptures. Some bacteria avoid the effect of penicillin by the production of penicillinase, an enzyme that destroys penicillin. Antibiotic use selects for populations of these antibiotic-resistant pathogens.

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