|
Complete Listing:Biological Sciences
Arts & Music
Audiobooks
Biographies & Memoirs
Business & Investing
Children's Books
Computers & Internet
Cooking, Food & Wine
Entertainment
Health, Mind & Body
History
Home & Garden
Horror
Literature & Fiction
Mystery & Thrillers
Nonfiction
Parenting & Families
Reference
Religion & Spirituality
Romance
Science & Nature
Science Fiction & Fantasy
Sports & Outdoors
Travel
Young Adult |
 Principles of Molecular Virologyby Alan J. Cann.
"Excellent...The writing flows easily with good practical examples...An attractive, up-to-date book." - Society for General Microbiology Quarterly
Viruses have properties that are distinct from other living organisms and so require different methods to culture them. This volume provides a broad treatment of the principles and practice of virus culture and will be of interest to all those involved in virus culture including academic, industrial, and clinical research groups. Contains over 90 tried and tested protocols. The properties of viruses are distinct from those of living organisms, making
the study of viruses different from other areas of biology. DNA Viruses:A Practical
Approach brings together all the major experimental methods for studying DNA viruses,
and will be of interest to all those working on DNA viruses, whether in academia,
industry or clinical research. Contains 150 tried and tested protocols.
RNA Viruses is wide ranging in scope, from core methods to emerging technology
such as reverse genetics and retrovirus vectors. Chapter one covers the fundamentals
of investigating RNA virus genome structure at a molecular level. Chapters two and
three describe techniques for mutagenesis of RNA genomes and analysis of transcription.
Chapter four deals with RNA virus-encoded proteinases, an important aspect of the
control of RNA virus gene expression. Chapter five considers retrovirus oncogenesis
and chapter six analysis of RNA virus quasispecies. Chapter seven describes systems
for investigation of in vitro replication of positive-stranded viruses and chapter
eight the packaging of RNA virus genomes. In addition to the technical aspects of
reverse genetics and retrovirus vectors, both of the final two chapters also consider
ethical aspects of these new technologies. All protocols are provided in easy to follow
step format with full listing of equipment and reagents required. These methods really
work. To encourage success, the authors also list useful hints and tips, discuss potential
problems and present typical data. No other methods manual in this field is as comprehensive
in its support. The book is therefore highly recommended for all researchers who work
on RNA viruses.
DNA viruses have always been the most important model systems for eukaryotic DNA
replication. Add to this the clinical significance of these human pathogens - 99%
of the population of the world is infected with at least one of the viruses discussed
in this volume - and it is difficult to overstate the importance of this group.
Also:
With the emergence of so many new diseases, understanding how viruses emerged and
evolved is vital in our on-going battle against them. Origin and Evolution of Viruses
is an invaluable reference source of general viral concepts and specific viral systems,
providing an excellent foundation to our understanding of how viruses emerge. The
reader is taken on a journey (in time and concepts) from the first primitive and basic
viral forms to their present-day complex counterparts. This unique and comprehensive
work is essential reading for all researchers in virology, molecular biology and related
areas, as well as evolutionary biologists interested in phylogenetic approaches to
molecular evolution.
"With the arrival of Retroviruses, a worthy successor to the 1985 classic has
finally appeared. Despite its downsized title everything about this volume, edited
by John Coffin, Stephen Hughes, and Harold Varmus, is top notch. Especially noteworthy
are the many superb illustrations, which include color diagrams of protein structures,
molecular mechanisms, and other aspects of retroviruses and their effects." - Science
There is a recurring theme in Klitzman's book: when an epidemic strikes, whether in an industrialized society or in a Stone Age tribe, responses are the same: denial and a refusal to alter ingrained behaviors that are responsible for spreading the pathogen. According to Klitzman, in all three (kuru, mad cow disease, and AIDS), people at risk feared the disease but had difficulty understanding the disease mechanisms, accepting long incubation periods, and changing deeply rooted behaviors. Among these behaviors were the eating of human flesh, the eating of beef, the practice of unsafe sex, and the use of dirty needles to inject narcotics and other drugs.
|
|
|
DNA
Virus Replication: Frontiers in Molecular Biology
Encyclopedia
of Virology